20 Biggest Upsets of 2018

9. Tampa Bay Buccaneers Beat the New Orleans Saints

In retrospect, this was the biggest upset of the NFL season as the Tampa Bay Buccaneers beat the New Orleans Saints in a 48-40 shootout.

Ryan Fitzpatrick completing 21 of 28 passes for 421 yards, four touchdowns and no interceptions as he outdueled Drew Brees.

Since that Week 1 matchup the Saints are 13-2, including a meaningless loss in Week 17 in which Drew Brees sat out. On the other hand, the Buccaneers went 4-11 after upsetting the Saints.