3. SF 49ers (+1400)
Wow, the 49ers had one unlucky season with a parade of injuries last year. With a fully healthy squad the 49ers are a real problem, especially their defense. Which was one of the reasons they were so bad last season because of how banged up their starting defense was. Jimmy Garoppolo also struggled last season but GM John Lynch hinted Jimmy G would be starting for the 49ers in 2021. The 49ers were in the Super Bowl only 2 seasons ago and almost hanging on to win. The 49ers are going to bounce back big time in 2021.